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PSMs were first described as a pro-inflammatory molecule. [2] This role has been repeatedly demonstrated to be true. PSMs are able to induce the production of a variety of cytokines as well as induce neutrophils to migrate to sites of infection. [3] PSMε in S. epidermidis is known to influence the production of IL-8. [3]
Staphylococcus epidermidis is a Gram-positive bacterium, and one of over 40 species belonging to the genus Staphylococcus. [1] It is part of the normal human microbiota , typically the skin microbiota , and less commonly the mucosal microbiota and also found in marine sponges.
Within the healed epidermis they will be replaced by keratinocytes originating from the epidermis. [29] [30] At the opposite, epidermal keratinocytes, can contribute to de novo hair follicle formation during the healing of large wounds. [31] Functional keratinocytes are needed for tympanic perforation healing. [32]
The epidermis, "epi" coming from the Greek language meaning "over" or "upon", is the outermost layer of the skin. It forms the waterproof, protective wrap over the body's surface, which also serves as a barrier to infection and is made up of stratified squamous epithelium with an underlying basal lamina.
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermal layer provides a barrier to infection from environmental pathogens [ 2 ] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss .
These results clearly indicate that GF mice have an impaired capacity of response in front of infections compared to SPF mice. Finally, mono-association of GF mice with S. epidermidis clearly restored immunity function which in the case of skin is mediated by IL-1 which is key for the restoration of IL-17A and IFN-γ levels. Thus skin ...
NAD is a molecule found in every living cell of the body that plays an important role in creating energy in the body. ... “Unlike in the energy transmission function, when acting as a messenger ...
The molecule of collagen XXIII can be found either in membrane-bond form or in shed form. Type XXIII collagen is expressed in both adult tissues and developing organs. It can be found in the epidermis and other epithelia such as those in tongue, gut and lung, but also in the brain, the kidney and the cornea.