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Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [2] [3] [4]Salts of this anion, especially docusate sodium, are widely used in medicine as an emollient laxative and as stool softeners, by mouth or rectally. [1]
Stool softener laxatives: Colace (docusate sodium) works in a different way by making it easier for water and lipids to penetrate the stool, softening it in its own way.
[9] [10] In 2022, the combination with docusate was the 261st most commonly prescribed medication in the United States, with more than 1 million prescriptions. [9] [11] It is sold under a number of brand names including Ex-Lax and Senokot. [1]
Solutions of polyethylene glycol and electrolytes (sodium chloride, sodium bicarbonate, potassium chloride, and sometimes sodium sulfate) are used for whole bowel irrigation, a process designed to prepare the bowel for surgery or colonoscopy and to treat certain types of poisoning. Brand names for these solutions include GoLytely, GlycoLax ...
150 mg (50 mg iron) with Docusate Sodium 100 mg* Ferrous Fumarate with DSS® Timed Capsules: Vita-Rx Tablets, extended-release, film-coated: 150 mg (50 mg iron) with Docusate Sodium 100 mg: Ferro-DSS® Caplets® Time-Caps Ferro-Sequels® Inverness
Klyx contains docusate sodium 1 mg/mL and sorbitol solution (70%)(crystallising) 357 mg/mL and is used for faecal impaction or constipation or for colon evacuation prior medical procedures, [44] developed by Ferring B.V. Micralax (not to be confused with MICROLAX®) [45]
ATC code A06 Drugs for constipation is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
A high volume example is sodium bis(2-ethylhexyl) sulfosuccinate. This is perhaps best known as the laxative docusate, however its main use is as a surfactant for which it finds common use in personal-care and household-care products, often under the name Aerosol-OTs. [1]
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