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Drugs or pharmaceutical agents inducing ototoxicity are regarded as ototoxic medications. Anatomy of the human ear. There is a wide range of ototoxic medications, for example, antibiotics, antimalarials, chemotherapeutic agents, non-steroidal anti-inflammatory drugs (NSAIDs) and loop diuretics. [2]
Ototoxicity of gentamicin can be exploited to treat some individuals with Ménière's disease by destroying the inner ear, which stops the vertigo attacks but causes permanent deafness. [19] Due to the effects on mitochondria, certain inherited mitochondrial disorders result in increased sensitivity to the toxic effects of aminoglycosides.
Otitis interna, or labyrinthitis, involves the inner ear. The inner ear includes sensory organs for balance and hearing. When the inner ear is inflamed, vertigo is a common symptom. Other symptoms in adults include pain and drainage from ear or problems with hearing. [8] Symptoms in children can include excessive crying, touching at ears ...
The main symptoms are severe vertigo and nystagmus. The most common symptom of vestibular neuritis is the onset of vertigo that has formed from an ongoing infection or trauma. [9] The dizziness sensation that is associated with vertigo is thought to be from the inner ear labyrinth. [10]
It can also be a sign of an inner ear infection or problems with blood supply to the inner ear. In some cases, vertigo may be a symptom of a stroke . Some additional causes of vertigo include:
Management of ear pain depends on the cause. If there is a bacterial infection, antibiotics are sometimes recommended and over the counter pain medications can help control discomfort. [7] Some causes of ear pain require a procedure or surgery. [7] [8] [9] 83 percent of children have at least one episode of a middle ear infection by three years ...
Once the infections resolve and hearing thresholds return to normal, childhood otitis media may still cause minor and irreversible damage to the middle ear and cochlea. [81] More research on the importance of screening all children under 4 years old for otitis media with effusion needs to be performed.
Antibiotics for ear infections are prescribed for infections that are recurrent or difficult for the body to clear. Antibiotic ear drops should be used as prescribed. Do not stop the use of medication even if the infection appears cleared because remaining bacteria can cause the infection to return. [23]
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