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The chemoreceptor trigger zone (CTZ) is an area of the medulla oblongata that receives inputs from blood-borne drugs or hormones, and communicates with other structures in the vomiting center to initiate vomiting. The CTZ is located within the area postrema, which is on the floor of the fourth ventricle and is outside of the blood–brain ...
The chemoreceptor trigger zone is within the area postrema of the medulla oblongata in which many types of chemical stimulation can provoke nausea and vomiting. This area was first identified and named in 1951 by Herbert L. Borison and Kenneth R. Brizzee. [6] Parts of cells, rather than parts of the body, can also behave as trigger zones.
The chemoreceptor trigger zone is an area of the medulla in the brain that receives inputs from blood-borne drugs or hormones, and communicates with the vomiting center (area postrema) to induce vomiting. [citation needed] Primary cilia play important roles in chemosensation.
The area postrema, a paired structure in the medulla oblongata of the brainstem, [1] is a circumventricular organ having permeable capillaries and sensory neurons that enable its dual role to detect circulating chemical messengers in the blood and transduce them into neural signals and networks.
The medulla oblongata or simply medulla is a long stem-like structure which makes up the lower part of the brainstem. [1] It is anterior and partially inferior to the cerebellum . It is a cone-shaped neuronal mass responsible for autonomic (involuntary) functions, ranging from vomiting to sneezing . [ 2 ]
Medulla oblongata. Medullary pyramids; Arcuate nucleus; Olivary body. Inferior olivary nucleus; Rostral ventrolateral medulla; Caudal ventrolateral medulla; Solitary nucleus (Nucleus of the solitary tract) Respiratory center-Respiratory groups. Dorsal respiratory group; Ventral respiratory group or Apneustic centre. Pre-Bötzinger complex ...
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The area postrema is located in the caudal medulla oblongata near the junction of the brainstem and the spinal cord. [16] In humans and in most other mammals that have been studied, it consists of swellings on either wall of the fourth ventricle. [16] [17] In rodents and lagomorphs, however, the area postrema forms a midline structure dorsal to ...