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They also carry a high risk of damage to surrounding ocular tissue. Accordingly, vitreolysis is not widely practised, being performed by very few specialists. One of them, John Karickhoff, has performed the procedure more than 1,400 times and claims a 90 percent success rate. [30]
A less invasive procedure is pneumatic vitreolysis. [6] This approach may be more cost effective and has a low reported rate of post-procedure side effects or complications. [6] Vitreolysis using an enzymatic (enzymatic vitreolysis) approach may also be used, however, this is more costly and may be associated with more adverse effects. [6]
Pharmacologic vitreolysis is an improvement over invasive surgery as it induces complete separation, creates a more physiologic state of the vitreomacular interface, prevents the development of fibrovascular membranes, is less traumatic to the vitreous, and is potentially prophylactic.
Researchers from Mass General Brigham, a health care system in Boston, Massachusetts, shared with Fox News Digital some of the scientific developments and breakthroughs they expect to see in 2025.
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Ocriplasmin, sold under the brand name Jetrea, is a recombinant protease with activity against fibronectin and laminin, components of the vitreoretinal interface.It is used for treatment of symptomatic vitreomacular adhesion, for which it received FDA approval on 17 October 2012.
The vitreous body (vitreous meaning "glass-like"; from Latin vitreus 'glassy', from vitrum 'glass' and -eus) is the clear gel that fills the space between the lens and the retina of the eyeball (the vitreous chamber) in humans and other vertebrates.
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