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  2. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    Low to moderate doses of CBD might reduce some of the paranoia, anxiety, [18] and reduction of hippocampal volumes that the current high potency THC marijuana (in the last decades, THC content increased and CBD content decreased) can cause, if the CBD substitutes a part of the THC dose.

  3. Kava - Wikipedia

    en.wikipedia.org/wiki/Kava

    Kava or kava kava (Piper methysticum: Latin 'pepper' and Latinized Greek 'intoxicating') is a plant in the pepper family, native to the Pacific Islands. [1]

  4. List of psychoactive plants - Wikipedia

    en.wikipedia.org/wiki/List_of_psychoactive_plants

    Cannabis plants vary widely, with different strains producing dynamic balances of cannabinoids (THC, CBD, etc.) and yielding markedly different effects. Popular strains are often hybrids of C. sativa and C. indica. The medicinal effects of cannabis are widely studied, and are active topics of research both at universities and private research ...

  5. Nabiximols - Wikipedia

    en.wikipedia.org/wiki/Nabiximols

    Nabiximols [2] sold under the brand name Sativex, is a specific Cannabis extract that was approved in 2010 as a botanical drug in the United Kingdom. Nabiximols is sold as a mouth spray intended to alleviate neuropathic pain , spasticity , overactive bladder , and other symptoms of multiple sclerosis ; it was developed by the UK company GW ...

  6. Recreational drug use - Wikipedia

    en.wikipedia.org/wiki/Recreational_drug_use

    Chart of drug dependence potential and relationship between use and lethal dose [33] Chart of relative harmfulness of some psychoactive substances [32] Drug harmfulness is defined as the degree to which a psychoactive drug has the potential to cause harm to the user and is measured in several ways, such as by addictiveness and the potential for ...

  7. Methysticin - Wikipedia

    en.wikipedia.org/wiki/Methysticin

    Methysticin is one of the six major kavalactones found in the kava plant. [1] Research suggests that methysticin and the related compound dihydromethysticin have CYP1A1 inducing effects which may be responsible for their toxicity. [2]

  8. Tetrahydrocannabinol - Wikipedia

    en.wikipedia.org/wiki/Tetrahydrocannabinol

    The median lethal dose of THC in humans is not fully known as there is conflicting evidence. A 1972 study gave up to 90 mg/kg of THC to dogs and monkeys without any lethal effects. A 1972 study gave up to 90 mg/kg of THC to dogs and monkeys without any lethal effects.

  9. Cannabis consumption - Wikipedia

    en.wikipedia.org/wiki/Cannabis_consumption

    Cannabis consumption refers to the variety of ways cannabis is consumed, among which inhalation (smoking and vaporizing) and ingestion are most common. All consumption methods involve heating the plant's THCA to decarboxylate it into THC, either at the time of consumption or during preparation.