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Proximal diabetic neuropathy, also known as diabetic amyotrophy, is a complication of diabetes mellitus that affects the nerves that supply the thighs, hips, buttocks and/or lower legs. Proximal diabetic neuropathy is a type of diabetic neuropathy characterized by muscle wasting, weakness, pain, or changes in sensation/numbness of the leg.
The diagnosis is considered in people who develop pain or numbness in a leg or foot with a history of diabetes. Muscle weakness, pain, balance loss, and lower limb dysfunction are the most common clinical manifestations. [7] Physical exam findings may include changes in appearance of the feet, presence of ulceration, and diminished ankle reflexes.
Moreover, foot surgery is well tolerated without anaesthesia. [2] The feet's insensivity to pain can easily be established by 512 mN quantitative pinprick stimulation. [3] In diabetes, peripheral nerve dysfunction can be combined with peripheral artery disease (PAD) causing poor blood circulation to the extremities (diabetic angiopathy). [4]
Dr. Tarr adds that recurring cramps can sometimes be a sign of circulation issues, but there would usually be other signs along with the toe cramps, including cramps in your calves and upper legs.
The causes of leg cramps at night can range from nutrient deficiency to tough workouts. Here, experts break down how to prevent and get rid of leg cramps. ... Sign in. Mail. 24/7 Help. For premium ...
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Nocturnal leg cramps are involuntary muscle contractions that occur in the calves, soles of the feet, or other muscles in the body during the night or (less commonly) while resting. The duration of nocturnal leg cramps is variable, with cramps lasting anywhere from a few seconds to several minutes.
Charley horses have many possible causes directly resulting from high or low pH or substrate concentrations in the blood, including hormonal imbalances, dehydration, low levels of magnesium, potassium, or calcium (evidence has been mixed), [5] [6] [7] side effects of medication, or, more seriously, diseases such as amyotrophic lateral sclerosis and neuropathy. [8]
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