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In gastroenterology, esophageal pH monitoring is the current gold standard for diagnosis of gastroesophageal reflux disease (GERD). It provides direct physiologic measurement of acid in the esophagus and is the most objective method to document reflux disease, assess the severity of the disease and monitor the response of the disease to medical or surgical treatment.
The condition was first described in a series of 20 patients at the Karolinska Institutet by Carlos Rubio in 2006. [3] Much of the reports of the condition over the subsequent several years were focused on ascertaining whether lymphocytic esophagitis was a true condition, and if it was, establishing uniform criteria for its diagnosis. [1] [2] [4]
Esophageal cancer is the eighth-most frequently-diagnosed cancer worldwide, [2] and because of its poor prognosis, it is the sixth most-common cause of cancer-related deaths. [55] It caused about 400,000 deaths in 2012, accounting for about 5% of all cancer deaths (about 456,000 new cases were diagnosed, representing about 3% of all cancers).
In older patients (60 or older), an endoscopy is often the next step in finding out the cause of newly onset indigestion regardless of the presence of alarm symptoms. [1] However, for all patients regardless of age, an official diagnosis requires symptoms to have started at least 6 months ago with a frequency of at least once a week over the ...
It can be caused by or associated with gastroesophageal reflux disease, [1] esophagitis, a dysfunctional lower esophageal sphincter, disordered motility, lye ingestion, or a hiatal hernia. Strictures can form after esophageal surgery and other treatments such as laser therapy or photodynamic therapy. While the area heals, a scar forms, causing ...
Research shows that up to 60% of the weight loss from prescription medications may come from lean body mass. Muscle loss can affect strength and mobility, so eating enough protein to preserve lean ...
The American Institute for Cancer Research recommends limiting red meat intake to 12-18 ounce per week. Steak has many nutrients, but here's why you should avoid overconsumption Skip to main content
A definitive diagnosis of EoE is based on the presence of at least 15 eosinophils/HPF in the esophageal biopsies of patients with exclusion of other causes of eosinophilia in the esophagus including gastroesophageal reflux disease (GERD), achalasia hypereosinophilic syndrome, Crohn's disease, infections, pill esophagitis, or graft vs host ...