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[1] [4] Complications can include swelling of the brain or lungs, seizures, low blood sugar, or cardiac arrest. [1] While usually due to aspirin, other possible causes include oil of wintergreen and bismuth subsalicylate. [2] Excess doses can be either on purpose or accidental. [1] Small amounts of oil of wintergreen can be toxic. [2]
Aspirin is non-selective and irreversibly inhibits both forms [4] (but is weakly more selective for COX-1 [5]). It does so by acetylating the hydroxyl of a serine residue at the 530 amino acid position. [6] Normally COX produces prostaglandins, most of which are pro-inflammatory, and thromboxanes, which promote clotting.
Numbness and tingling in an arm or leg [1] [2] Paleness [1] [2] of the skin of the arm or leg; Muscle weakness of an arm or leg, [1] [2] possibly to the grade of paralysis [2] Later symptoms are closely related to infarction of the tissue supplied by the occluded artery: Blisters of the skin in the affected area [1] Shedding of skin ...
Swollen legs, feet, and ankles. Swollen abdomen. More frequent urination at night. Lack of appetite and nausea. Fatigue. Feet and hands feel colder than other parts of the body. Problems concentrating
Most commonly, the legs or arms are affected. [1] Symptoms may include skin that feels tight, the area feeling heavy, and joint stiffness. [1] Other symptoms depend on the underlying cause. [2] Causes may include venous insufficiency, heart failure, kidney problems, low protein levels, liver problems, deep vein thrombosis, infections ...
Symptoms classically affect a leg and typically develop over hours or days, [20] though they can develop suddenly or over a matter of weeks. [21] The legs are primarily affected, with 4–10% of DVT occurring in the arms. [11] Despite the signs and symptoms being highly variable, [5] the typical symptoms are pain, swelling, and redness.
For a small number of people, taking aspirin can result in symptoms including hives, swelling, and headache. [205] Aspirin can exacerbate symptoms among those with chronic hives, or create acute symptoms of hives. [206] These responses can be due to allergic reactions to aspirin, or more often due to its effect of inhibiting the COX-1 enzyme.
Like other medications for the treatment of (ED), Cialis — and its generic version, tadalafil — can cause adverse effects at first. Fortunately, most tadalafil side effects are mild and ...
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