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An allele [1], or allelomorph, is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule. [2]Alleles can differ at a single position through single nucleotide polymorphisms (SNP), [3] but they can also have insertions and deletions of up to several thousand base pairs.
Allopatric speciation (from Ancient Greek ἄλλος (állos) 'other' and πατρίς (patrís) 'fatherland') – also referred to as geographic speciation, vicariant speciation, or its earlier name the dumbbell model [1]: 86 – is a mode of speciation that occurs when biological populations become geographically isolated from each other to an extent that prevents or interferes with gene flow.
A genetic isolate is a population of organisms that has little to no genetic mixing with other organisms of the same species due to geographic isolation or other factors that prevent reproduction.
In biology, a cline is a measurable gradient in a single characteristic (or biological trait) of a species across its geographical range. [1] Clines usually have a genetic (e.g. allele frequency, blood type), or phenotypic (e.g. body size, skin pigmentation) character.
Population structure (also called genetic structure and population stratification) is the presence of a systematic difference in allele frequencies between subpopulations. In a randomly mating (or panmictic) population, allele frequencies are expected to be roughly similar between groups. However, mating tends to be non-random to some degree ...
Allelic heterogeneity is the phenomenon in which different mutations at the same locus lead to the same or very similar phenotypes.These allelic variations can arise as a result of natural selection processes, as a result of exogenous mutagens, genetic drift, or genetic migration.
There are two distinctive mapping approaches used in the field of genome mapping: genetic maps (also known as linkage maps) [7] and physical maps. [3] While both maps are a collection of genetic markers and gene loci, [8] genetic maps' distances are based on the genetic linkage information, while physical maps use actual physical distances usually measured in number of base pairs.
Constitutive monoallelic expression occurs from the same specific allele throughout the whole organism or tissue, as a result of genomic imprinting. [5] RME is a broader class of monoallelic expression, which is defined by random allelic choice in somatic cells , so that different cells of the multi-cellular organism express different alleles.
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