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  2. Prochirality - Wikipedia

    en.wikipedia.org/wiki/Prochirality

    In stereochemistry, prochiral molecules are those that can be converted from achiral to chiral in a single step. [1] [2] An achiral species which can be converted to a chiral in two steps is called proprochiral. [2] If two identical substituents are attached to an sp 3-hybridized atom, the descriptors pro-R and pro-S are used to distinguish ...

  3. Absolute configuration - Wikipedia

    en.wikipedia.org/wiki/Absolute_configuration

    Chiral molecules can differ in their chemical properties, but are identical in their physical properties, which can make distinguishing enantiomers challenging. Absolute configurations for a chiral molecule (in pure form) are most often obtained by X-ray crystallography , although with some important limitations.

  4. Chirality - Wikipedia

    en.wikipedia.org/wiki/Chirality

    Instead, both effects can also occur when the propagation direction of the electromagnetic wave together with the structure of an (achiral) material form a chiral experimental arrangement. [10] [11] This case, where the mutual arrangement of achiral components forms a chiral (experimental) arrangement, is known as extrinsic chirality. [12] [13]

  5. Chirality (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Chirality_(chemistry)

    An achiral molecule having chiral conformations could theoretically form a mixture of right-handed and left-handed crystals, as often happens with racemic mixtures of chiral molecules (see Chiral resolution#Spontaneous resolution and related specialized techniques), or as when achiral liquid silicon dioxide is cooled to the point of becoming ...

  6. Chiral media - Wikipedia

    en.wikipedia.org/wiki/Chiral_media

    Helices, chiral characteristics (properties), chiral media, [2] order, and symmetry all relate to the concept of left- and right-handedness. [ 3 ] [ 4 ] Types of chirality

  7. Cahn–Ingold–Prelog priority rules - Wikipedia

    en.wikipedia.org/wiki/Cahn–Ingold–Prelog...

    When an achiral nucleophile attacks acetone, both faces are identical and there is only one reaction product. When the nucleophile attacks butanone, the faces are not identical (enantiotopic) and a racemic product results. When the nucleophile is a chiral molecule diastereoisomers are formed.

  8. Topicity - Wikipedia

    en.wikipedia.org/wiki/Topicity

    Enantiotopic groups are identical and indistinguishable except in chiral environments. For instance, the CH 2 hydrogens in ethanol (CH 3 CH 2 OH) are normally enantiotopic, but can be made different (diastereotopic) if combined with a chiral center, for instance by conversion to an ester of a chiral carboxylic acid such as lactic acid, or if coordinated to a chiral metal center, or if ...

  9. Chiral drugs - Wikipedia

    en.wikipedia.org/wiki/Chiral_drugs

    An achiral environment does not differentiate the molecular twins whereas a chiral environment does distinguish the left-handed version from the right-handed version. Human body, a classic bio-environment, is inherently handed as it is filled with chiral discriminators like amino acids, enzymes, carbohydrates, lipids, nucleic acids, etc.