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The use of fetal tissue in vaccine development is the practice of researching, developing, and producing vaccines through growing viruses in cultured (laboratory-grown) cells that were originally derived from human fetal tissue. [1] Since the cell strains in use originate from abortions, [2] there has been opposition to the practice and the ...
HEK 293 cells. Human embryonic kidney 293 cells, also often referred to as HEK 293, HEK-293, 293 cells, are an immortalised cell line derived from HEK cells isolated from a female fetus in the 1970s. [1][2] The HEK 293 cell line has been widely used in research for decades due to its reliable and fast growth and propensity for transfection.
WI-38 cells (Left: in high density. Right: in low density) WI-38 is a diploid human cell line composed of fibroblasts derived from lung tissue of a 3-month-gestation female fetus. [1][2] The fetus came from the elective abortion of a Swedish woman in 1963. The cell line was isolated by Leonard Hayflick the same year, [3][4] and has been used ...
Pfizer’s coronavirus vaccine is now being distributed — first to medical workers and vulnerable groups, then to the general public — in the United States. Moderna’s product is expected to ...
MRC-5. MRC-5 (Medical Research Council cell strain 5) is a diploid cell culture line composed of fibroblasts, originally developed from the lung tissue of a 14-week-old aborted Caucasian male fetus. [1][2] The cell line was isolated by J.P. Jacobs and colleagues in September 1966 from the seventh population doubling of the original strain, and ...
The cell surface antigens most commonly used to identify hES cells are the glycolipids stage specific embryonic antigen 3 and 4, and the keratan sulfate antigens Tra-1-60 and Tra-1-81. The molecular definition of a stem cell includes many more proteins and continues to be a topic of research. [29]
Cell-based vaccine. Cell-based vaccines are developed from mammalian or more rarely avian or insect cell lines rather than the more common method which uses the cells in embryonic chicken eggs to develop the antigens. [1] The potential use of cell culture techniques in developing viral vaccines has been widely investigated in the 2000s as a ...
Microchimerism. During pregnancy, a two-way traffic of immune cells may occur through the placenta. Exchanged cells can multiply and establish long-lasting cell lines that are immunologically active even decades after giving birth. Microchimerism is the presence of a small number of cells in an individual that have originated from another ...