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  2. Amyloid-beta precursor protein - Wikipedia

    en.wikipedia.org/wiki/Amyloid-beta_precursor_protein

    Amyloid-beta precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. It functions as a cell surface receptor [ 5 ] and has been implicated as a regulator of synapse formation , [ 6 ] neural plasticity , [ 7 ] antimicrobial activity, [ 8 ] and iron export . [ 9 ]

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    Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!

  4. Presenilin-2 - Wikipedia

    en.wikipedia.org/wiki/Presenilin-2

    19165 Ensembl ENSG00000143801 ENSMUSG00000010609 UniProt P49810 Q61144 RefSeq (mRNA) NM_000447 NM_012486 NM_001128605 NM_011183 RefSeq (protein) NP_000438 NP_036618 NP_001122077 NP_035313 Location (UCSC) Chr 1: 226.87 – 226.93 Mb Chr 1: 180.05 – 180.09 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Presenilin-2 is a protein that (in humans) is encoded by the PSEN2 gene. Function ...

  5. List of built-in iOS apps - Wikipedia

    en.wikipedia.org/wiki/List_of_built-in_iOS_apps

    The App Store is a digital distribution platform which allows users to browse and download apps developed with Apple's iOS Software Development Kit. The App Store opened on July 10, 2008, with the release of IPhone OS 2 , launching with 500 applications available.

  6. Amyloid-beta precursor protein secretase - Wikipedia

    en.wikipedia.org/wiki/Amyloid-beta_precursor...

    BACE is a transmembrane protein with an extracellular aspartic acid protease domain. γ-secretase is actually a protein complex containing presenilin, nicastrin, APH-1, and PEN-2. Presenilin is believed to harbor the protease domain and represents an important example of an uncommon type of protease that cleaves targets within the cell membrane.

  7. Download and install the AOL app on iOS

    help.aol.com/articles/aol-app-downloading-and...

    Learn more about the AOL app and download it from the App Store. The AOL app is available for iOS devices running iOS 12 or newer. Open the App Store on your device. Tap the Search icon. Type "AOL" in the search field. Tap Search. Next to "AOL: News Email Weather Video", tap Get. Enter your Touch ID or Apple ID, if prompted. Tap Open.

  8. Beta-secretase 1 - Wikipedia

    en.wikipedia.org/wiki/Beta-secretase_1

    Beta-secretase 1, also known as beta-site amyloid precursor protein cleaving enzyme 1, beta-site APP cleaving enzyme 1 (BACE1), membrane-associated aspartic protease 2, memapsin-2, aspartyl protease 2, and ASP2, is an enzyme that in humans is encoded by the BACE1 gene. [5] Expression of BACE1 is observed mainly in neurons and oligodendrocytes. [6]

  9. Alpha secretase - Wikipedia

    en.wikipedia.org/wiki/Alpha_secretase

    Alpha secretases are a family of proteolytic enzymes that cleave amyloid precursor protein (APP) in its transmembrane region.Specifically, alpha secretases cleave within the fragment that gives rise to the Alzheimer's disease-associated peptide amyloid beta when APP is instead processed by beta secretase and gamma secretase.

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