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A 2017 hybrid systematic review reported that data from 50 studies on androgen levels with spironolactone in women were equivocal. [67] A 1993 review reported that changes in hormone levels with spironolactone were very heterogeneous, with most changes not achieving significance. [16]
High doses of spironolactone, which are needed for considerable antiandrogenic effects, are not recommended for men due to the high risk of feminization and other side effects. Spironolactone can be used to treat symptoms of hyperandrogenism , such as due to polycystic ovary syndrome .
And because PCOS affects many hormones (example: estrogen) that are responsible for a variety of bodily functions, women with PCOS may also find it hard to become pregnant.
A steroidogenesis inhibitor, also known as a steroid biosynthesis inhibitor, is a type of drug which inhibits one or more of the enzymes that are involved in the process of steroidogenesis, the biosynthesis of endogenous steroids and steroid hormones. [1]
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Unlike spironolactone, bicalutamide has no antimineralocorticoid activity, [97] and for this reason, has no risk of hyperkalemia (which can, rarely/in severe cases, result in hospitalization or death) [112] or other antimineralocorticoid side effects such as urinary frequency, dehydration, hypotension, hyponatremia, metabolic acidosis, or ...
Estrogen, alongside other hormones, works to optimize the efficiency of your bodily functions. But an imbalance in hormones — like low estrogen levels — can affect many things, from your drive ...
They work by mainly suppressing luteinising hormone (LH) and follicle-stimulating hormone (FSH) and in turn preventing ovulation. [1] The pill, patch, and vaginal ring are all about 93% effective with typical use. [5] Beneficial health effects include reduced risks of ovarian, endometrial and colorectal cancers.
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