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A wide range of symptoms can indicate if a person has polymyalgia rheumatica. The classic symptoms include: [10] Pain and stiffness (moderate to severe) in the neck, shoulders, upper arms, thighs, and hips, which inhibits activity, especially in the morning/after sleeping. Pain can also occur in the groin area and in the buttocks.
The main differential diagnosis is polymyalgia rheumatica (PMR), although pain, stiffness and weakness at the level of the shoulders and pelvic girdle with associated systemic symptoms (fever, malaise, fatigue, weight loss) is more typical of PMR.
[4] [7] Symptoms may include headache, pain over the temples, flu-like symptoms, double vision, and difficulty opening the mouth. [3] Complications can include blockage of the artery to the eye with resulting blindness, as well as aortic dissection, and aortic aneurysm. [4] GCA is frequently associated with polymyalgia rheumatica. [4]
Polymyalgia rheumatica (or "muscle rheumatism") is an inflammatory condition that mainly occurs in the elderly; it is associated with giant-cell arteritis (It often responds to prednisolone). [18] Polymyositis is an autoimmune condition in which the muscle is affected. [19] Rhabdomyolysis is the breakdown of muscular tissue due to any cause ...
Myalgia or muscle pain is a painful sensation evolving from muscle tissue.It is a symptom of many diseases.The most common cause of acute myalgia is the overuse of a muscle or group of muscles; another likely cause is viral infection, especially when there has been no injury.
Polymyalgia rheumatica: Large to medium vessels in shoulders, hips None specific Possible [43] Urticarial vasculitis: Small vessels in skin C1q antibodies Probable [44] Vasculitis: All vessel sizes in multiple organs Depends on specific type Uncertain [45]
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In cardiology, genetic conditions such as Brugada syndrome can share features with related disorders caused by mutations in the same gene.An overlap syndrome can be seen whereby a mutation in the SCN5A gene encoding the cardiac sodium channel causes a reduction in the peak sodium current leading to the typical ECG features of Brugada syndrome, but which simultaneously increases the sustained ...