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Individuals with Addison's disease have more than a doubled mortality rate. [37] Furthermore, individuals with Addison's disease and diabetes mellitus have an almost four-fold increase in mortality compared to individuals with only diabetes. [38] The risk ratio for cause mortality in males and females is 2.19 and 2.86, respectively. [37]
The disease can cause dangerously low cortisol levels, ... It can also cause hyperpigmentation, or a darkening of the skin that can make people appear bronzed. ... Addison's disease is treatable ...
The most common cause of primary adrenal insufficiency (Addison's disease) overall is autoimmune adrenalitis. [2] The prevalence of Addison's disease ranges from 5 to 221 per million in different countries. [30] In children, congenital adrenal hyperplasia (CAH) is the most common cause of adrenal insufficiency, with an incidence 1 in 14,200 ...
"Hyperpigmentation just means darkening of the skin," says Dr. Dowling. "So basically, 'hyperpigmentation' is an umbrella term for lots of different conditions that cause hyperpigmentation ...
Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [2] such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas.
Hyperpigmentation is associated with a number of diseases or conditions, including the following: Addison's disease and other sources of adrenal insufficiency , in which hormones that stimulate melanin synthesis, such as melanocyte-stimulating hormone (MSH), are frequently elevated.
These are the best products for hyperpigmentation—tested by editors, dermatologists, and experts—to help get rid of acne scars, melasma, and sun spots. These Products are the IRL Ctrl+Alt ...
Hyperpigmentation results from an increase in melanin synthesis, which is mostly brought on by sun exposure, dermatological disorders, hormones, aging, genetic factors, skin injuries or inflammation, and acne. Sun exposure, which greatly increases the synthesis of melanin, is the most common cause of hyperpigmentation. [4]