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Somatic damage may refer to any of the health effects of radiation other than teratogenesis, including Acute radiation syndrome; Radiation burns; Radiation-induced ...
Radiation damage is the effect of ... High doses of ionizing radiation can cause damage to living tissue such as ... owing to mutation of somatic cells or heritable ...
Larger radiation doses are more prone to cause tighter clustering of damage, and closely localized damage is increasingly less likely to be repaired. [39] Somatic mutations cannot be passed down from parent to offspring, but these mutations can propagate in cell lines within an organism. Radiation damage can also cause chromosome and chromatid ...
Ionizing radiation has been known to cause damage to cellular components such as proteins, lipids, and nucleic acids. It has also been known to cause DNA double-strand breaks. Accumulation of DNA double strand breaks can lead to cell cycle arrest in somatic cells and cause cell death.
Dose rates high enough to cause the acute form (> ~0.1 Gy/h) are fatal long before onset of the chronic form. The lower threshold for chronic radiation syndrome is between 0.7 and 1.5 Gy, at dose rates above 0.1 Gy/yr. [3] This condition is primarily known from the Kyshtym disaster, where 66 cases were diagnosed.
This is due to the high relative biological effectiveness of alpha radiation to cause biological damage after alpha-emitting radioisotopes enter living cells. Ingested alpha emitter radioisotopes such as transuranics or actinides are an average of about 20 times more dangerous, and in some experiments up to 1000 times more dangerous than an ...
There is a threshold dose which causes clinical radiation damage of cells in the body. [5] As the dose increases, the severity of injury increases. [5] This also impairs tissue recovery. [5] The IRCP also describes how cancer develops following radiation exposure. [5] This happens via DNA damage response processes. [5]
The reported health effects are consistent with high doses of radiation, and comparable to the experiences of cancer patients undergoing radio-therapy [15] but have many other potential causes. [14] The effects included "metallic taste, erythema, nausea, vomiting, diarrhea, hair loss, deaths of pets, farm and wild animals, and damage to plants."