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A further consequence of damage to the endothelium is the release of pathological quantities of von Willebrand factor, which promote platelet aggregation and adhesion to the subendothelium, and thus the formation of potentially fatal thrombi. Angiosarcoma is cancer of the endothelium and is rare with only 300 cases per year in the US. [29]
Excitotoxicity can occur from substances produced within the body (endogenous excitotoxins).Glutamate is a prime example of an excitotoxin in the brain, and it is also the major excitatory neurotransmitter in the central nervous system of mammals. [14]
The blood–brain barrier is formed by the brain capillary endothelium and excludes from the brain 100% of large-molecule neurotherapeutics and more than 98% of all small-molecule drugs. [28] Overcoming the difficulty of delivering therapeutic agents to specific regions of the brain presents a major challenge to treatment of most brain disorders.
All these nutrients play an important role in brain health and protecting your brain cells from damage. Salmon. Add fish to your brain health grocery list — fatty fish, that is. This includes ...
To combine several brain-boosting foods into a single meal, Dr. Kelley recommends a walnut pesto with spinach and a great virgin olive oil. Related: The Best Nut for Your Brain Health, According ...
Relatively speaking, the brain consumes an immense amount of energy in comparison to the rest of the body. The mechanisms involved in the transfer of energy from foods to neurons are likely to be fundamental to the control of brain function. [1] Human bodily processes, including the brain, all require both macronutrients, as well as ...
In turn, the brain is more vulnerable to ischemic insults as there is a dysregulation in the supply of blood and oxygen. [19] More specifically, hypertension inflicts damage to small resistance arteries, which supply nutrients to the internal capsule, brainstem, thalamus, cerebellum, and basal ganglia, and cause cell death and tissue ...
"In reality," he said, "foodborne illnesses can lead to severe and long-lasting health issues, hospitalization or even death, especially for vulnerable populations like the immunocompromised ...