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Chimney sweeps' cancer, also called soot wart or scrotal cancer, is a squamous cell carcinoma of the scrotum. It has the distinction of being the first reported form of occupational cancer, and was initially identified by Percivall Pott in 1775. [1] It was initially noticed as being prevalent amongst chimney sweeps.
Percivall Pott, engraved from an original picture by Nathaniel Dance-Holland, National Library of Medicine, Images from the History of Medicine.. Percivall Pott (6 January 1714, in London – 22 December 1788) was an English surgeon, one of the founders of orthopaedics, and the first scientist to demonstrate that cancer may be caused by an environmental carcinogen, namely chimney sweeps ...
Occupational cancer is cancer caused by occupational hazards. Several cancers have been directly tied to occupational hazards, including chimney sweeps' carcinoma , mesothelioma , and others. Types of hazards
Mule spinners' cancer or mule-spinners' cancer was a cancer, an epithelioma of the scrotum. It was first reported in 1887 in a cotton mule spinner . [ 1 ] In 1926, a British Home Office committee strongly favoured the view that this form of cancer was caused by the prolonged action of mineral oils on the skin of the scrotum, and of these oils ...
The first cause of cancer was identified by British surgeon Percivall Pott, who discovered in 1775 that cancer of the scrotum was a common disease among chimney sweeps. [ citation needed ] The work of other individual physicians led to various insights, but when physicians started working together they could draw firmer conclusions.
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Studies conducted before smoking and lung cancer were scientifically related connected a higher rate of smoking to lung cancer incidence, and eventually mortality 20 years later. [2] In 1775, Percivall Pott’s discovery of the high incidence of scrotal cancer in chimney sweeps demonstrated that charred organic substances were carcinogenic.
1900 – Swedish Dr. Stenbeck cures a skin cancer with small doses of radiation [4]; 1920s – Dr. William B. Coley's immunotherapy treatment, regressed tumors in hundreds of cases, the success of Coley's Toxins attracted heavy resistance from his rival and supervisor, Dr. James Ewing, who was an ardent supporter of radiation therapy for cancer.