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Chimney sweeps' cancer, also called soot wart or scrotal cancer, is a squamous cell carcinoma of the scrotum. It has the distinction of being the first reported form of occupational cancer, and was initially identified by Percivall Pott in 1775. [1] It was initially noticed as being prevalent amongst chimney sweeps.
Percivall Pott, engraved from an original picture by Nathaniel Dance-Holland, National Library of Medicine, Images from the History of Medicine.. Percivall Pott (6 January 1714, in London – 22 December 1788) was an English surgeon, one of the founders of orthopaedics, and the first scientist to demonstrate that cancer may be caused by an environmental carcinogen, namely chimney sweeps ...
In 1775, Percivall Pott’s discovery of the high incidence of scrotal cancer in chimney sweeps demonstrated that charred organic substances were carcinogenic. Wynder used Pott’s research as a foundation for his argument that his hypothesis that smoking leads to the development of lung cancer was biologically valid. [3]
Occupational cancer is cancer caused by occupational hazards. Several cancers have been directly tied to occupational hazards, including chimney sweeps' carcinoma , mesothelioma , and others. Types of hazards
Sidney Farber is regarded as the father of modern chemotherapy.. Cancer research has been ongoing for centuries. Early research focused on the causes of cancer. [1] Percivall Pott identified the first environmental trigger (chimney soot) for cancer in 1775 and cigarette smoking was identified as a cause of lung cancer in 1950.
Mule spinners' cancer or mule-spinners' cancer was a cancer, an epithelioma of the scrotum. It was first reported in 1887 in a cotton mule spinner . [ 1 ] In 1926, a British Home Office committee strongly favoured the view that this form of cancer was caused by the prolonged action of mineral oils on the skin of the scrotum, and of these oils ...
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The first cause of cancer was identified by British surgeon Percivall Pott, who discovered in 1775 that cancer of the scrotum was a common disease among chimney sweeps. [ citation needed ] The work of other individual physicians led to various insights, but when physicians started working together they could draw firmer conclusions.