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Central nervous system (CNS) depression is a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness, possibly leading to coma or death. It is the result of inhibited or suppressed brain activity .
Venlafaxine blocks the neuronal reuptake of serotonin, noradrenaline and, to a lesser extent, dopamine in the central nervous system. In contrast with several other antidepressant drugs, venlafaxine can induce a rapid onset of action mainly due to a subsequent norepinephrine reuptake inhibition. [ 24 ]
But in large doses, GHB activates the GABA B receptor, an inhibitory receptor in the central nervous system, which overpowers the excitatory effects, thus causing central nervous system depression. [95] [96] Some antipsychotics are agonists of the GHB receptor. [97] [98] [99] GHB can usually be found in either sodium, potassium, magnesium, or ...
They note that about 30% of people with depression do not adequately respond to treatment. They say the subtypes may help identify potential treatment responses for things such as antidepressants ...
A stimulant is a drug that stimulates the central nervous system, increasing arousal, attention and endurance. Stimulants are used in psychiatry to treat attention deficit-hyperactivity disorder. Because the medications can be addictive, patients with a history of drug abuse are typically monitored closely or treated with a non-stimulant.
Clonazepam, like other benzodiazepines, may impair a person's ability to drive or operate machinery. The central nervous system depressing effects of the drug can be intensified by alcohol consumption, so alcohol should be avoided while taking this medication. Benzodiazepines have been shown to cause dependence.
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