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  2. Proximal diabetic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Proximal_diabetic_neuropathy

    Proximal diabetic neuropathy, also known as diabetic amyotrophy, is a complication of diabetes mellitus that affects the nerves that supply the thighs, hips, buttocks and/or lower legs. Proximal diabetic neuropathy is a type of diabetic neuropathy characterized by muscle wasting, weakness, pain, or changes in sensation/numbness of the leg.

  3. Inclusion body myositis - Wikipedia

    en.wikipedia.org/wiki/Inclusion_body_myositis

    Weakness comes on slowly (over months to years) in an asymmetric manner and progresses steadily, leading to severe weakness and wasting of arm and leg muscles. IBM is more common in men than women. [10] Patients may become unable to perform activities of daily living and most require assistive devices within 5 to 10 years of symptom onset.

  4. Inflammatory myopathy - Wikipedia

    en.wikipedia.org/wiki/Inflammatory_myopathy

    The usual criteria for a diagnosis of PM are weakness in muscles of the head, neck, trunk, upper arms or upper legs; raised blood serum concentrations of some muscle enzymes such as creatine kinase; unhealthy muscle changes on electromyography; and biopsy findings of (i) muscle cell degeneration and regeneration and (ii) chronic inflammatory ...

  5. Hoover's sign (leg paresis) - Wikipedia

    en.wikipedia.org/wiki/Hoover's_sign_(leg_paresis)

    Involuntary extension of the "normal" leg occurs when flexing the contralateral leg against resistance. To perform the test, the examiner should hold one hand under the heel of the "normal" limb and ask the patient to flex the contralateral hip against resistance (while the patient is supine), asking the patient to keep the weak leg straight while raising it.

  6. Nerve compression syndrome - Wikipedia

    en.wikipedia.org/wiki/Nerve_compression_syndrome

    These paresthesias may be painful, such as shooting pain, burning, or a dull ache. They may also be pain-free, such as numbness or tingling. Motor nerve entrapment may present with muscle weakness or paralysis for voluntary movements of the innervated muscles. Entrapment of certain pelvic nerves can cause incontinence and/or sexual dysfunction. [2]

  7. Neuromuscular disease - Wikipedia

    en.wikipedia.org/wiki/Neuromuscular_disease

    Symptoms of neuromuscular disease may include numbness, paresthesia, muscle atrophy, a pseudoathletic appearance, exercise intolerance, myalgia (muscle pain), fasciculations (muscle twitches), myotonia (delayed muscle relaxation), hypotonia (lack of resistance to passive movement), fixed muscle weakness (a static symptom), or premature muscle ...

  8. Frailty syndrome - Wikipedia

    en.wikipedia.org/wiki/Frailty_syndrome

    Muscle weakness makes it difficult to perform everyday activities, like getting into a bathtub. Sarcopenia is the degenerative loss of skeletal muscle mass, quality, and strength associated with aging. [19] The rate of muscle loss is dependent on exercise level, co-existing health conditions, nutrition and other factors.

  9. Muscle weakness - Wikipedia

    en.wikipedia.org/wiki/Muscle_weakness

    Muscle weakness can also be classified as either "proximal" or "distal" based on the location of the muscles that it affects. Proximal muscle weakness affects muscles closest to the body's midline, while distal muscle weakness affects muscles further out on the limbs. Proximal muscle weakness can be seen in Cushing's syndrome [18] and ...