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Lipoatrophia semicircularis, also known as semicircular lipoatrophy, [1] is a medical condition in humans, commonly known as ribbed thighs. It consists of a semicircular zone of atrophy of the subcutaneous fatty tissue located mostly on the front of the thighs .
In this measurement, skinfold thickness of less than 10 millimetres (0.39 in) for men and 22 millimetres (0.87 in) for women at the anterior thigh is suggestive cutoff for the diagnosis of lipodystrophy. [7] Less commonly, biphotonic absorptiometry and magnetic resonance imaging (MRI) can be done for the measurement of body fat. [5]
The diagnosis is a clinical one, usually established by an experienced endocrinologist.Using a skinfold caliper to measure skinfold thickness in various parts of the body or a total body composition scan using Dual-energy X-ray Absorptiometry may also help identify the subtype.
Common cardiovascular problems related to this syndrome are cardiac hypertrophy and arterial hypertension (high blood pressure). [8] This disorder can also cause metabolic syndrome. Most with the disorder also have a prominent umbilicus or umbilical hernia. Commonly, patients will also have acromegaly with enlargement of the hands, feet, and ...
Symptoms that patients may experience when bone disorders form can include bone deformities, hip pain, overgrowing of bone in an individual's skull which can result in headaches and a loss of hearing, pain and numbness in arm or legs if the spine is affected and an overall weakness in the body particularly in the hip and knee joints.
Lipoatrophy is the term describing the localized loss of fat tissue. This may occur as a result of subcutaneous injections of insulin in the treatment of diabetes , from the use of human growth hormone or from subcutaneous injections of copaxone used for the treatment of multiple sclerosis .
Familial partial lipodystrophy, also known as Köbberling–Dunnigan syndrome, [2] is a rare genetic metabolic condition characterized by the loss of subcutaneous fat. [3]: 495
Diagnosis involves interviewing the patient and performing physical exams. When attempting to establish the cause of the arthralgia, the emphasis is on the interview. [2] The patient is asked questions intended to narrow the number of potential causes. Given the varied nature of these possible causes, some questions may seem irrelevant.