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Whole body computed tomography scans (i.e. CT scans) frequently find enlarged mesenteric lymph nodes (i.e. lymph nodes attached to the intestinal mesentery) and may show evidence of liver, spleen, and/or other organ involvement in cases which are advancing or have advanced to a malignant lymphoma.
Lymph node metastasis is the spread of cancer cells into a lymph node.. Lymph node metastasis is different from malignant lymphoma.Lymphoma is a cancer of lymph node, rather than cancer in the lymph node, because lymphoma originates from the lymph node itself, instead of originating elsewhere (e.g., the breast or colon) and spreading to the lymph nodes.
The predictive value and prevalence of lymphovascular invasion is strongly dependent on the type of cancer. In other words, LVI in one type of cancer may be much less important than LVI in another type of cancer. Generally speaking, it is associated with lymph node metastases [2] [3] which themselves are predictive of a poorer prognosis. [4]
A liver metastasis is a malignant tumor in the liver that has spread from another organ that is affected by cancer. The liver is a common site for metastatic disease because of its rich, dual blood supply (the liver receives blood via the hepatic artery and portal vein). Metastatic tumors in the liver are 20 times more common than primary liver ...
If cancer has spread to the lymph nodes or distant organs, which is the case with Stage III and Stage IV colon cancer respectively, adding chemotherapy agents fluorouracil, capecitabine or oxaliplatin increases life expectancy. If the lymph nodes do not contain cancer, the benefits of chemotherapy are controversial.
N0: No evidence of spread to regional lymph nodes. N1a: Tumor cells found in 1 regional lymph node. N1b: Tumor cells found in 2 or 3 regional lymph nodes. N1c: There are cancerous nodules near the colon that do not appear to be lymph nodes. N2a: Tumor cells found in 4 to 6 regional lymph nodes. N2b: Tumor cells found in 7 or more regional lymph ...
The most common form of colon cancer is adenocarcinoma, constituting between 95% [2] and 98% [3] of all cases of colorectal cancer. Other, rarer types include lymphoma, adenosquamous and squamous cell carcinoma. Some subtypes have been found to be more aggressive. [4]
Colorectal cancer may metastasise to the inferior mesenteric lymph nodes. For this reason, the inferior mesenteric artery may be removed in people with lymph node-positive cancer. [3] This has been proposed since at least 1908, by surgeon William Ernest Miles. [4]