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1,3-Bisphosphoglyceric acid (1,3-Bisphosphoglycerate or 1,3BPG) is a 3-carbon organic molecule present in most, if not all, living organisms.It primarily exists as a metabolic intermediate in both glycolysis during respiration and the Calvin cycle during photosynthesis. 1,3BPG is a transitional stage between glycerate 3-phosphate and glyceraldehyde 3-phosphate during the fixation/reduction of ...
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Print/export Download as PDF; Printable version; In other projects Wikidata item; Appearance. ... 1,3-Bisphosphoglycerate (1,3-BPG) 2,3-Bisphosphoglycerate (2,3-BPG)
Better Portable Graphics, a file format for coding digital images; Big Spring McMahon–Wrinkle Airport (FAA location identifier), near Big Spring, Texas; Bisphosphoglycerate, a molecule with two biologically important isomers: 1,3-Bisphosphoglyceric acid, a metabolite in glycolysis; 2,3-Bisphosphoglyceric acid, regulates hemoglobin
Phosphoglycerate kinase (EC 2.7.2.3) (PGK 1) is an enzyme that catalyzes the reversible transfer of a phosphate group from 1,3-bisphosphoglycerate (1,3-BPG) to ADP producing 3-phosphoglycerate (3-PG) and ATP : 1,3-bisphosphoglycerate + ADP ⇌ glycerate 3-phosphate + ATP. Like all kinases it is a transferase. PGK is a major enzyme used in ...
His 11: the nucleophile of the 1,2-BPG to 1,3-BPG reaction. Rotates back and forth with the help of His-188 to get in an in-line position in order to attack the 1’ phosphate group. [3] His-188: involved in overall stability of protein, [4] as well as hydrogen bonding to substrate, as His-11, which it pulls into its catalytic position.
2,3-BPG is formed from 1,3-BPG by the enzyme BPG mutase.It can then be broken down by 2,3-BPG phosphatase to form 3-phosphoglycerate.Its synthesis and breakdown are, therefore, a way around a step of glycolysis, with the net expense of one ATP per molecule of 2,3-BPG generated as the high-energy carboxylic acid-phosphate mixed anhydride bond is cleaved by 2,3-BPG phosphatase.