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Phosphofructokinase-1 (PFK-1) is one of the most important regulatory enzymes (EC 2.7.1.11) of glycolysis. It is an allosteric enzyme made of 4 subunits and controlled by many activators and inhibitors. PFK-1 catalyzes the important "committed" step of glycolysis, the conversion of fructose 6-phosphate and ATP to fructose 1,6-bisphosphate and ...
The model equations follow the principles of mass transport, fluid dynamics, and biochemistry in order to simulate the fate of a substance in the body. [9] Compartments are usually defined by grouping organs or tissues with similar blood perfusion rate and lipid content (i.e. organs for which chemicals' concentration vs. time profiles will be similar).
In cell biology, protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family.
K is the clearance [mL/min] or [m 3 /s] C is the concentration [mmol/L] or [mol/m 3 ] (in the United States often [mg/mL]) From the above definitions it follows that d C d t {\displaystyle {\frac {dC}{dt}}} is the first derivative of concentration with respect to time, i.e. the change in concentration with time.
The distinction between the two Hill equations is whether they measure occupancy or response. The Hill equation reflects the occupancy of macromolecules: the fraction that is saturated or bound by the ligand. [1] [2] [nb 1] This equation is formally equivalent to the Langmuir isotherm. [3]
The Frenkel–Kontorova (FK) model is a fundamental model of low-dimensional nonlinear physics. [ 1 ] The generalized FK model describes a chain of classical particles with nearest neighbor interactions and subjected to a periodic on-site substrate potential. [ 2 ]
The trajectories are allowed to 'hop' between various adiabatic states at certain times such that the quantum amplitudes for the adiabatic states follow the time dependent Schrödinger equation. The probability of these hops are dependent on the coupling between the states, and is generally significant only in the regions where the difference ...
Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phosphocreatine kinase, is an enzyme (EC 2.7.3.2) expressed by various tissues and cell types.CK catalyses the conversion of creatine and uses adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP).