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The Wiley Protocol is a form of bioidentical hormone replacement therapy (BHRT) devised and advocated by author T. S. Wiley.The protocol claims to relieve the symptoms of menopause but is also promoted as increasing overall health through the recreation of a pre-menopausal woman's monthly hormonal cycle using rhythmic doses of hormones standardized to a uniform purity.
Deborah Moskowitz published an article suggesting that some forms of bioidentical hormones may be safer than non-bioidentical hormones in safety and effectiveness, [58] though this review was criticized for "[attempting] to demonstrate that BHT has a good safety profile, but the data presented only serve to demonstrate similar risks to ...
Hormone replacement therapy (HRT), also known as menopausal hormone therapy or postmenopausal hormone therapy, is a form of hormone therapy used to treat symptoms associated with female menopause. [ 1 ] [ 2 ] Effects of menopause can include symptoms such as hot flashes , accelerated skin aging, vaginal dryness , decreased muscle mass , and ...
Specifically, most ratings are determined from multivariate logistic regressions of medical outcomes at a given healthcare provider to risk-adjust the patients and 1-, 3- and 5-star awards are given to providers whose negative outcomes are worse than expected, near predicted levels, and better than expected, respectively.
A review of selected studies reported a range of mean peak estradiol levels of 24 to 140 pg/mL occurring 1 to 12 hours after administration of 2 mg oral estradiol valerate. [4] A study found that, in accordance with their differences in molecular weights, oral estradiol produced higher levels of estradiol than oral estradiol valerate. [ 109 ]
It is the most commonly used form of estrogen in menopausal hormone therapy in the United States. [ 12 ] [ 13 ] However, it has begun to fall out of favor relative to bioidentical estradiol , which is the most widely used form of estrogen in Europe for menopausal hormone therapy.
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