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Pazopanib, sold under the brand name Votrient, is an anti-cancer medication marketed worldwide by Novartis. It is a potent and selective multi-targeted receptor tyrosine kinase inhibitor that blocks tumour growth and inhibits angiogenesis .
Tumour pain †; Myelosuppression † [Note 3]; Underactive thyroid; Dehydration; Low level of phosphate in the blood; Dizziness; Lethargy; Paraesthesia; Peripheral sensory neuropathy
Pazopanib is a multi-targeted tyrosine kinase receptor inhibitor. The structure is formed by indazole, pyrimidine and a benzene ring. [23] If the indazole ring is kept the same, replacing 5-amino-2-methylbenzenesulfonamide with another arylamine at position 2 of the pyrimidine, gives inhibitory effect on VEGFR-2 and c-Kit.
Capivasertib, sold under the brand name Truqap, is an anti-cancer medication used for the treatment of breast cancer. [4] [7] It is taken by mouth.[4]The most common adverse reactions include diarrhea, cutaneous adverse reactions, increased random glucose, decreased lymphocytes, decreased hemoglobin, increased fasting glucose, nausea, fatigue, decreased leukocytes, increased triglycerides ...
Crizotinib, sold under the brand name Xalkori among others, is an anti-cancer medication used for the treatment of non-small cell lung carcinoma (NSCLC). [2] [3] [4 ...
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Larotrectinib, sold under the brand name Vitrakvi, is a medication for the treatment of cancer. [1] [5] [7] It is an inhibitor of tropomyosin kinase receptors TrkA, TrkB, and TrkC.
Ovarian cancer is a cancerous tumor of an ovary. [10] It may originate from the ovary itself or more commonly from communicating nearby structures such as fallopian tubes or the inner lining of the abdomen.
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