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Excessive amounts or intake can result in weakness, headache, nausea, constipation, urinary tract infections, and abdominal pain. [7] [12] Serious side effects may include high blood calcium and anaphylaxis. [7] Calcitriol was identified as the active form of vitamin D in 1971 and the drug was approved for medical use in the United States in ...
The active vitamin D metabolite, calcitriol, exerts its biological effects by binding to the vitamin D receptor (VDR), which is primarily located in the nuclei of target cells. [ 1 ] [ 14 ] When calcitriol binds to the VDR, it enables the receptor to act as a transcription factor , modulating the gene expression of transport proteins involved ...
Vitamin D3, also called cholecalciferol, is what gives the “sunshine” vitamin its name. D3 is produced in our body from exposure to sunlight, Prest explains. Vitamin D2 vs. D3 Uses. Both ...
Not only are there tablets and gel caps and gummies in different dosages and paired with minerals, ... Vitamin D2 vs. vitamin D3. ... But if someone needs a bolus dose (that is, a very high dose ...
Cholecalciferol is a form of vitamin D which is naturally synthesized in skin and functions as a pro-hormone, being converted to calcitriol. This is important for maintaining calcium levels and promoting bone health and development. [4] As a medication, cholecalciferol may be taken as a dietary supplement to prevent or to treat vitamin D ...
“Vitamin D3 cholecalciferol is the most absorbable and potent form, [whereas] Vitamin D2 (ergocalciferol) is typically plant-based and not as effective at raising vitamin D levels in the body ...
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