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This toner takes skin-brightening to the next level by pairing kojic acid with vitamin C — yet another tyrosinase inhibitor — as well as bearberry extract, a plant-based alternative to ...
α-Arbutin directly inhibits the enzymatic activity of tyrosinase, which is essential for melanin synthesis. Tyrosinase catalyzes the first two steps in melanin production: the hydroxylation of tyrosine to l-DOPA and the oxidation of l-DOPA to dopaquinone. By inhibiting tyrosinase, α-arbutin reduces the formation of melanin in melanocytes. [5]
Tyrosinase is a highly conserved protein in animals and apparently arose already in bacteria. The tyrosinase related protein (Tyrp1) and dopachrome tautomerase (Dtc), which encode for protein implicated in melanin synthesis which are the common regulatory elements of exon/intron structure.
However, over the past year, I tested hundreds of products and found a few stellar new-to-me anti-aging skin-care products, along with hair masks and hair dryers that have transformed my middle ...
The weight loss list is focused on the most effective eating plans for losing weight and sustaining weight loss, while the best overall diet prioritizes weight management and healthy eating. Here ...
In the absence of albinism or hyperpigmentation, the human epidermis contains approximately 74% eumelanin and 26% pheomelanin, largely irrespective of skin tone, with eumelanin content ranging between 71.8–78.9%, and pheomelanin varying between 21.1–28.2%. [7]
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