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Hexavalent chromium (chromium(VI), Cr(VI), chromium 6) is any chemical compound that contains the element chromium in the +6 oxidation state (thus hexavalent). [1] It has been identified as carcinogenic, which is of concern since approximately 136,000 tonnes (150,000 tons) of hexavalent chromium were produced in 1985. [ 2 ]
IARC group 1 Carcinogens are substances, chemical mixtures, and exposure circumstances which have been classified as carcinogenic to humans by the International Agency for Research on Cancer (IARC). [1] This category is used when there is sufficient evidence of carcinogenicity in humans.
Hexavalent chromium is a toxic metal, known to cause several health problems and is a carcinogen. Exposure to hexavalent chromium can cause irritation and problems in the respiratory tract, stomach, and small intestine. It is linked to several cancers, such as lung cancer, oral cancer, and intestinal cancer. [11]
Hexavalent chromium compounds can be toxic and carcinogenic (IARC Group 1). Inhaling particles of hexavalent chromium compounds can cause lung cancer. Also positive associations have been observed between exposure to chromium (VI) compounds and cancer of the nose and nasal sinuses. [11]
PG&E used chromium 6, or hexavalent chromium (a cheap and efficient rust suppressor), in its compressor station for natural-gas transmission pipelines. [1] [3] Hexavalent-chromium compounds are genotoxic carcinogens. In 1993, legal clerk Erin Brockovich began an investigation into the health impacts of the contamination. A class-action lawsuit ...
Chromium toxicity refers to any poisonous toxic effect in an organism or cell that results from exposure to specific forms of chromium—especially hexavalent chromium. [1] Hexavalent chromium and its compounds are toxic when inhaled or ingested. Trivalent chromium is a trace mineral that is essential to human nutrition.
Articles in this category are about agents that are listed in the International Agency for Research on Cancer's corresponding group (List of IARC Group 1 Agents - Carcinogenic to humans), and should contain agents according to the IARC's current published list.
Chromium, especially hexavalent chromium, is highly toxic to fish because it is easily absorbed across the gills, readily enters blood circulation, crosses cell membranes and bioconcentrates up the food chain. In contrast, the toxicity of trivalent chromium is very low, attributed to poor membrane permeability and little biomagnification. [141]