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Nizoral shampoo can help with dandruff and fungal infections, and it’s even been linked to hair growth. However, one uncommon Nizoral shampoo side effect includes alopecia (hair loss).
The side effects of ketoconazole are sometimes harnessed in the treatment of non-fungal conditions. While ketoconazole blocks the synthesis of the sterol ergosterol in fungi, in humans, at high dosages (>800 mg/day), it potently inhibits the activity of several enzymes necessary for the conversion of cholesterol to steroid hormones such as ...
The yeast-like cells of Malassezia, measuring between 1.5–4.5 μm by 3–7 μm, are characterised as phialides featuring tiny collarettes (a small, collar-like flange or lip at the mouth of a phialide from which spores or conidia are produced and released).
These investigations show that the Malassezia species causing most skin disease in humans, including the most common cause of dandruff and seborrhoeic dermatitis, is M. globosa (though M. restricta is also involved). [1] The skin rash of tinea versicolor (pityriasis versicolor) is also due to infection by this fungus.
“The fungus feeds off the skin’s sebum and excretes end products onto the scalp which can irritate the scalp skin, resulting in dandruff and its symptoms like dryness, itch, and flaking ...
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff, seborrhoeic dermatitis and eczema. [2] Climbazole has shown a high in vitro and in vivo efficacy against Malassezia spp. that appear to play an important role in the pathogenesis of dandruff. [2]
The symptoms of dandruff vs dry scalp can look and feel similar, but causes and treatments differ. Experts explain the difference between the two conditions. What Dermatologists Want You to Know ...
Malassezia furfur is a fungus that lives on the superficial layers of the dermis.It generally exists as a commensal organism forming a natural part of the human skin microbiota, but it can gain pathogenic capabilities when morphing from a yeast to a hyphal form during its life cycle, through unknown molecular changes. [2]
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