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It stimulates the acinar cells of the pancreas to release a juice rich in pancreatic digestive enzymes (hence an alternate name, pancreozymin) that catalyze the digestion of fat, protein, and carbohydrates. Thus, as the levels of the substances that stimulated the release of CCK drop, the concentration of the hormone drops as well.
Bile flows from the liver through the bile ducts and into the gall bladder for storage. The bile is released in response to cholecystokinin (CCK), a peptide hormone released from the duodenum. The production of CCK (by endocrine cells of the duodenum) is stimulated by the presence of fat in the duodenum.
Some components are synthesized by hepatocytes (liver cells); the rest are extracted from the blood by the liver. [3] Bile is secreted by the liver into small ducts that join to form the common hepatic duct. [4] Between meals, secreted bile is stored in the gallbladder. [5] During a meal, the bile is secreted into the duodenum (part of the ...
When the pyloric sphincter valve opens, partially digested food enters the duodenum where it mixes with digestive enzymes from the pancreas and bile juice from the liver and then passes through the small intestine, in which digestion continues. When the chyme is fully digested, it is absorbed into the blood. 95% of nutrient absorption occurs in ...
Since bile increases the absorption of fats, it is an important part of the absorption of the fat-soluble substances, [10] such as the vitamins A, D, E, and K. [11] Besides its digestive function, bile serves also as the route of excretion for bilirubin, a byproduct of red blood cells recycled by the liver.
Small intestine, pancreas: Inhibits insulin secretion Galanin: Enteric nerves: Ghrelin: Stomach: Stimulates appetite, increases gastric emptying Glucagon-like peptide 1: Pancreas, ileum: Increases insulin secretion Glucagon-like peptide 2: Ileum, colon: Enterocyte-specific growth hormone Growth factors: Throughout the gut: Cell proliferation ...
Acinar cells are stimulated by cholecystokinin (CCK), which is a hormone/neurotransmitter produced by the intestinal cells (I cells) in the duodenum. CCK stimulates production of the pancreatic zymogens. Pancreatic juice, composed of the secretions of both ductal and acinar cells, contains the following digestive enzymes: [11]
Endocrine I cells of the small intestine; neurons of the brain and gut Gallbladder, pancreas, gastric smooth muscle None Stimulates pancreatic enzyme and HCO3- secretion Stimulates gallbladder contraction; inhibits stomach emptying Satiety Fatty acids and some amino acids Secretin: Endocrine S cells of the small intestine Pancreas, stomach None