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The predominant symptoms of hypercalcemia are abdominal pain, constipation, extreme thirst, excessive urination, kidney stones, nausea and vomiting. [ 3 ] [ 14 ] In severe cases where the calcium concentration is >14 mg/dL, individuals may experience confusion, altered mental status, coma, and seizure.
The combination of PTHrP driven osteoclast activation and calcium reabsorption by the kidneys causes hypercalcemia associated with malignancy (humoral type). [22] Another mechanism in which cancer causes hypercalcemia is via local osteolysis due to metastasis to bone. [22]
That allows bacteria and metabolites from the gut that are toxic to other organs to spill out into the bloodstream, where they can cause inflammation that leads to heart, liver and kidney disease ...
However, excessive ingestion of calcium of more than 10-15 g per day has been reported to cause calcium levels too high for renal calcitriol suppression to control, resulting in net calcium absorption that ultimately causes hypercalcemia. [3] [10] Hypercalcemia affects the kidneys in multiple ways that altogether contributes to hypovolemia.
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Coloboma of the eye, heart defects, atresia of the nasal choanae, retarded growth & or development, genital abnormalities, ear abnormalities CHD Congenital heart disease: CHD Congenital hip dysplasia: CHD Coronary heart disease: CHF Congestive heart failure: CIDP Chronic inflammatory demyelinating polyneuropathy: CIPA
Constipation may have many causes, but it also has abundant remedies. Look to diet first when trying to reduce or relieve constipation, and consider consulting a physician if you feel symptoms are ...
Cardiorenal syndrome (CRS) is an umbrella term used in the medical field that defines disorders of the heart and kidneys whereby "acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other". [1] When one of these organs fails, the other may subsequently fail. [2]
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