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Cytokinesis illustration Ciliate undergoing cytokinesis, with the cleavage furrow being clearly visible. Cytokinesis (/ ˌ s aɪ t oʊ k ɪ ˈ n iː s ɪ s /) is the part of the cell division process and part of mitosis during which the cytoplasm of a single eukaryotic cell divides into two daughter cells.
The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.
This is an accepted version of this page This is the latest accepted revision, reviewed on 19 December 2024. Cell division producing haploid gametes For the figure of speech, see Meiosis (figure of speech). For the process whereby cell nuclei divide to produce two copies of themselves, see Mitosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...
The thick lines are chromosomes, and the thin blue lines are fibers pulling on the chromosomes and pushing the ends of the cell apart. The cell cycle in eukaryotes: I = Interphase, M = Mitosis, G 0 = Gap 0, G 1 = Gap 1, G 2 = Gap 2, S = Synthesis, G 3 = Gap 3. Cell division is the process by which a parent cell divides into two daughter cells. [1]
The primary result of mitosis and cytokinesis is the transfer of a parent cell's genome into two daughter cells. The genome is composed of a number of chromosomes—complexes of tightly coiled DNA that contain genetic information vital for proper cell function. [32]
Prophase is the initial phase when spindle fibers appear that function to move the chromosomes toward opposite poles. This spindle apparatus consists of microtubules, microfilaments and a complex network of various proteins. During metaphase, the chromosomes line up using the spindle apparatus in the middle of the cell along the equatorial plate.
MEN-mediated Cdk dephosphorylation is necessary for chromosome decondensation. [2] [5] In vertebrates, chromosome decondensation is initiated only after nuclear import is reestablished. If lamin transport through nuclear pores is prevented, chromosomes remain condensed following cytokinesis, and cells fail to reenter the next S phase. [16]
During the M phase, the chromosomes separate and cytokinesis occurs. The switches maintain the orderly progression of the cell cycle and act as checkpoints to ensure that each phase has been properly completed before progression to the next phase. [1]