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Pia mater (/ ˈ p aɪ. ə ˈ m eɪ t ər / or / ˈ p iː ə ˈ m ɑː t ər /), [1] often referred to as simply the pia, is the delicate innermost layer of the meninges, the membranes surrounding the brain and spinal cord. Pia mater is medieval Latin meaning "tender mother". [1] The other two meningeal membranes are the dura mater and the ...
The astrocytes of the glia limitans are responsible for separating the brain into two primary compartments. The first compartment is the immune-privileged brain and spinal cord parenchyma. This compartment contains multiple immunosuppressive cell surface proteins such as CD200 and CD95L and it allows for the release of anti-inflammatory factors.
The pia mater (Latin: tender mother) [9] is a very delicate membrane. It is the meningeal envelope that firmly adheres to the surfaces of the brain and spinal cord, following all of the brain's contours (gyri and sulci). It is a very thin membrane composed of fibrous tissue covered on its outer surface by a sheet of flat cells thought to be ...
The formation of the neural tube polarizes the neuroepithelial cells by orienting the apical side of the cell to face inward, which later becomes the ventricular zone, and the basal side is oriented outward, which contacts the pia, or outer surface of the developing brain. [3]
The leptomeningeal collateral circulation (also known as leptomeningeal anastomoses or pial collaterals) is a network of small blood vessels in the brain that connects branches of the middle, anterior and posterior cerebral arteries (MCA, ACA, and PCA), [1] with variation in its precise anatomy between individuals. [2]
The ependyma and vascular pia mater – the tela choroidea, form regions of minute projections known as a choroid plexus that projects into each ventricle. [ 1 ] [ 2 ] The choroid plexus produces most of the cerebrospinal fluid of the central nervous system that circulates through the ventricles of the brain, the central canal of the spinal ...
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Although the pia mater adheres to the surface of the brain, closely following the contours of its gyri and sulci, the arachnoid mater only covers its superficial surface, bridging across the gyri. This leaves wider spaces between the pia and arachnoid and the cavities are known as the subarachnoid cisterns. [citation needed]