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In a US study, after 10 years, 37% had developed into a defined connective tissue disease, 43% continued undifferentiated and 20% were in remission. [ 23 ] In a Spanish study, after a mean follow-up of 11±3 years, 14% had developed a definite CTD, 62% continued undifferentiated, and 24% were in remission.
Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone. [5] [6] It is believed to be the fourth leading cause of disability in the world, affecting 1 in 7 adults in the United States alone. [7]
The rate of progression is unpredictable, and the prognosis can be difficult. The disease may stabilize after a number of years, go into spontaneous remission, or in cases involving the chest and upper spine, prove fatal. Recurrence of the disease following remission can also occur. Involvement of the spine and skull base may cause a poor ...
Arthritis is predominantly a disease of the elderly, but children can also be affected by the disease. [102] Arthritis is more common in women than men at all ages and affects all races, ethnic groups and cultures. In the United States a CDC survey based on data from 2013 to 2015 showed 54.4 million (22.7%) adults had self-reported doctor ...
It is not always certain why arthritis of the knee develops. [citation needed] The knee may become affected by almost any form of arthritis, including those related to mechanical damage of the structures of the knee (osteoarthritis, and post-traumatic arthritis), various autoimmune forms of arthritis (including; rheumatoid arthritis, juvenile arthritis, and SLE-related arthritis, psoriatic ...
[7] [8] This pain is often described as weakness, but true weakness is not a part of this disease. People may also note a change in shape of the thumb. [7] [8] Some people choose surgery, but most people find they can accommodate trapeziometacarpal arthritis. [9] [10] [11]
Long-term follow-up studies have shown that MCTD can progress to a moderate disease with a favorable prognosis, or patients can acquire a significant condition with vascular alterations driven by pulmonary hypertension and increased mortality. Approximately one-third of people with MCTD have a benign course and go into remission, while the ...
The most common initial presenting symptom of wrist osteoarthritis is joint pain. [7] [8] Other signs and symptoms, as with any joint affected by osteoarthritis, include: Loss of motion stiffness, which can be worse after a period of rest, such as when one awakes in the morning. Deformity of the wrist.
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