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Leishmaniasis is a wide array of clinical manifestations caused by protozoal parasites of the Trypanosomatida genus Leishmania. [7] It is generally spread through the bite of phlebotomine sandflies , Phlebotomus and Lutzomyia , and occurs most frequently in the tropics and sub-tropics of Africa, Asia, the Americas, and southern Europe.
Leishmania / l iː ʃ ˈ m eɪ n i ə,-ˈ m æ n-/ [1] is a parasitic protozoan, a single-celled organism of the genus Leishmania that is responsible for the disease leishmaniasis. [ 2 ] [ 3 ] [ 4 ] They are spread by sandflies of the genus Phlebotomus in the Old World , and of the genus Lutzomyia in the New World .
79136 n/a Ensembl ENSG00000255552 n/a UniProt n a n/a RefSeq (mRNA) NM_001003721 NM_024123 n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a Wikidata View/Edit Human Lymphocyte antigen 6 complex, locus G6E (pseudogene) is a protein that in humans is encoded by the LY6G6E gene. Function LY6G6E belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major ...
Leishmaniavirus (also known as Leishmania RNA virus or LRV) is a genus of double-stranded RNA virus, in the family Totiviridae. Protozoa serve as natural hosts, and Leishmaniaviruses are present in several species of the human protozoan parasite Leishmania .
Ly6 proteins are characterized by the LU domain.Typically, they contain one LU domain, but some members of the family have multiple LU domains.The LU domain consists of 60-80 AA and contains 10 cysteines arranged in a specific pattern that allows the creation of 5 disulfide bridges which in turn allow the formation of a three-fingered (3F) structural motif.
Leishmania amazonensis is a parasite responsible for the disease leishmaniasis. This species has been known to spread by using sandflies as its vector and a vertebrate as its primary host, just like other species of Leishmania. [ 1 ]
Mucocutaneous leishmaniasis is an especially disturbing form of cutaneous leishmaniasis, because it produces destructive and disfiguring lesions of the face. It is most often caused by Leishmania braziliensis, but cases caused by L. aethiopica have also been described. [10] Mucocutaneous leishmaniasis is very difficult to treat.
Leishmania major is a species of parasite found in the genus Leishmania, and is associated with the disease zoonotic cutaneous leishmaniasis (also known as Aleppo boil, Baghdad boil, Bay sore, Biskra button, Chiclero ulcer, Delhi boil, Kandahar sore, Lahore sore, Oriental sore, Pian bois, and Uta). [1]