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The name "pyogenic granuloma" is misleading, as it is neither pyogenic or a true granuloma. Rather, it is a capillary hemangioma of lobular subtype, which is why such a lesion is prone to bleeding. [5] It is also not truly pyogenic (pus-producing), as the cause is hormonal or traumatic and has no association with infection or pus production.
This type of epulis is neither pyogenic ("pus producing") nor a true granuloma, but it is a vascular lesion.About 75% of all pyogenic granulomas occur on the gingiva, [2] growing beneath the gingival margin, [8] although they may also occur elsewhere in the mouth or other parts of the body (where the term epulis is inappropriate).
A peripheral ossifying fibroma, also known as ossifying fibrous epulis, is “a gingival nodule which is composed of a cellular fibroblastic connective tissue stroma which is associated with the formation of randomly dispersed foci of mineralised products, which consists of bone, cementum-like tissue, or a dystrophic calcification.
Pyogenic granuloma may occur elsewhere in the mouth such as the tongue and lips, but are not therefore epulides. Giant cell epulis, also known as peripheral giant cell granuloma, are like fibrous epulis and occur at the anterior interdental margin, the gum between the teeth at the front. They are more common in women.
Granuloma; Picture of a granuloma (without necrosis) as seen through a microscope on a glass slide: The tissue on the slide is stained with two standard dyes (hematoxylin: blue, eosin: pink) to make it visible. The granuloma in this picture was found in a lymph node of a patient with a Mycobacterium avium infection. Specialty: Pathology
English: Histopathology of pyogenic granuloma - high magnification. HE stain. Annotated are major features: Endothelial cell clusters, inflammation, variable amount of mitoses, and edema. - Christopher S. Hale, M.D.. Skin nonmelanocytic tumor - Vascular tumors - Capillary / pyogenic granuloma. PathologyOultines. Topic Completed: 1 August 2012.
Examples of granulation tissue can be seen in pyogenic granulomas and pulp polyps. Its histological appearance is characterized by proliferation of fibroblasts and thin-walled, delicate capillaries ( angiogenesis ), and infiltrated inflammatory cells in a loose extracellular matrix.
Peripheral giant-cell granuloma (PGCG) is an oral pathologic condition that appears in the mouth as an overgrowth of tissue due to irritation or trauma. Because of its overwhelming incidence on the gingiva, the condition is associated with two other diseases, pyogenic granuloma and peripheral ossifying fibroma. These three diseases are ...