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This story was reviewed by Mike Bohl, MD. In the ‘80s, researchers set out to test a medication called sildenafil citrate for treating high blood pressure and angina (chest pain) from heart disease.
Sildenafil’s ability to increase blood flow makes the medication useful for managing other conditions. Some sources suggest Viagra might make you last longer in bed, and others say it’s good ...
Research has found that taking Viagra does not increase high blood pressure. Sildenafil, the active ingredient in Viagra, is actually used to treat a certain kind of high blood pressure in the lungs.
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8]
These drugs work to increase blood flow necessary for arousal when you're stimulated. It's likely to experience some side effects with Viagra, like headaches, dizziness or nausea.
Sildenafil and other PDE-5 inhibitor medications can interact with other drugs, including several common medications used to treat chest pain, high blood pressure (sildenafil can cause low blood ...
When blood vessels dilate, the flow of blood is increased due to a decrease in vascular resistance and increase in cardiac output [further explanation needed]. Vascular resistance is the amount of force circulating blood must overcome in order to allow perfusion of body tissues. Narrow vessels create more vascular resistance, while dilated ...
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