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Atopic dermatitis (AD), also known as atopic eczema, is a long-term type of inflammation of the skin. [2] Atopic dermatitis is also often called simply eczema but the same term is also used to refer to dermatitis, the larger group of skin conditions. [2] [5] Atopic dermatitis results in itchy, red, swollen, and cracked skin. [2]
The terms dermatitis and eczema are sometimes used synonymously. [1] [14] However the term eczema is often used to specifically mean atopic dermatitis (also known as atopic eczema). [15] [7] Terminology might also differ according to countries. In some languages, dermatitis and eczema mean the same thing, while in other languages dermatitis ...
Atopic reactions are caused by localized hypersensitivity reactions to an allergen. Atopy appears to show a strong hereditary component. One study concludes that the risk of developing atopic dermatitis (3%) or atopy in general (7%) "increases by a factor of two with each first-degree family member already suffering from atopy". [14]
Atopic dermatitis is a chronic dermatitis associated with a hereditary tendency to develop allergies to food and inhalant substances. [46] [47] [48] Atopic dermatitis (atopic eczema, disseminated neurodermatitis, flexural eczema, infantile eczema, prurigo diathsique)
The allergic march (also called atopic march) is a medical term used to explain the natural history of atopic manifestations. The allergic march is characterized by some antibody responses to immunoglobulin E (IgE) and clinical symptoms that may appear in childhood, and continue for years or decades and often changing with age. [1]
"Distribution" refers to how lesions are localized. They may be confined to a single area (a patch) or may be in several places. Some distributions correlate with the means by which a given area becomes affected. For example, contact dermatitis correlates with locations where allergen has elicited an allergic immune response.
The Eczema Area and Severity Index (EASI) is a validated tool for the measurement of severity of atopic dermatitis.It ranges from 0 (no disease) to 72 (maximal disease). [1] [2] The EASI was developed in 1998 by modifying the Psoriasis Area and Severity Index (PASI), a widely accepted scoring system for psoriasis.
Erythroderma is generalized exfoliative dermatitis, which involves 90% or more of the patient's skin. [3] The most common cause of erythroderma is exacerbation of an underlying skin disease, such as Harlequin-type ichthyosis, psoriasis, contact dermatitis, seborrheic dermatitis, lichen planus, pityriasis rubra pilaris or a drug reaction, such as the use of topical steroids. [4]
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