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  2. Enzyme inhibitor - Wikipedia

    en.wikipedia.org/wiki/Enzyme_inhibitor

    An enzyme inhibitor is a molecule that binds to an enzyme and blocks its activity. Enzymes are proteins that speed up chemical reactions necessary for life, in which substrate molecules are converted into products. [1] An enzyme facilitates a specific chemical reaction by binding the substrate to its active site, a specialized area on the ...

  3. Phosphodiesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Phosphodiesterase_inhibitor

    Phosphodiesterase inhibitor. A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), thereby preventing the inactivation of the intracellular second messengers, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) by the respective PDE subtype (s).

  4. List of phosphodiesterase inhibitors - Wikipedia

    en.wikipedia.org/wiki/List_of_phosphodiesterase...

    Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Donate; Help; Learn to edit; Community portal; Recent changes; Upload file

  5. Category:Enzyme inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:Enzyme_inhibitors

    A. Acetaldehyde dehydrogenase inhibitors ‎ (25 P) Acetylcholine synthesis inhibitors ‎ (2 P) Alcohol dehydrogenase inhibitors ‎ (4 P) ATP synthase inhibitors ‎ (3 P)

  6. Exemestane - Wikipedia

    en.wikipedia.org/wiki/Exemestane

    Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women. The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by ...

  7. ACE inhibitor - Wikipedia

    en.wikipedia.org/wiki/ACE_inhibitor

    Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure. [1] [2] This class of medicine works by causing relaxation of blood vessels as well as a decrease in blood volume, which leads to lower blood pressure and decreased oxygen demand from the heart.

  8. Abemaciclib - Wikipedia

    en.wikipedia.org/wiki/Abemaciclib

    Abemaciclib, sold under the brand name Verzenio among others, is a medication for the treatment of advanced or metastatic breast cancers. It was developed by Eli Lilly and it acts as a CDK inhibitor selective for CDK4 and CDK6. [4] It was designated as a breakthrough therapy for breast cancer by the US Food and Drug Administration (FDA) in ...

  9. Activin and inhibin - Wikipedia

    en.wikipedia.org/wiki/Activin_and_inhibin

    Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Identified in 1986, [1][2] activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle. Many other functions have been found to be exerted by activin, including roles in cell ...

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