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Naloxone is an opioid antagonist: a medication used to reverse or reduce the effects of opioids. [13] For example, it is used to restore breathing after an opioid overdose. [13] Effects begin within two minutes when given intravenously, five minutes when injected into a muscle, [13] and ten minutes as a nasal spray. [14]
Narcan (Naloxone HCl Nasal Spray 4 mg) will be available for purchase over-the-counter starting in September, the drug's manufacturer Emergent BioSolutions Inc. announced Wednesday. The company's ...
It’s sold as a nasal spray under the brand name Narcan. Coming off a year with a record number of opioid-related overdose deaths in the United States — nearly 83,000 in 2022, ...
“Narcan can save a life in minutes, which is critical,” he said. The over-the-counter Narcan, which will be sold as a single dose given as a nasal spray, most likely won’t be available until ...
Nalmefene. Nalmefene is a medication that is used in the treatment of opioid overdose and alcohol dependence. [2][3] Nalmefene belongs to the class of opioid antagonists and can be taken by mouth, administered by injection, or delivered through nasal administration. [7]
A fentanyl nasal spray with a strength of 100 μg per use. The bioavailability of intranasal fentanyl is about 70–90%, but with some imprecision due to clotted nostrils, pharyngeal swallow, and incorrect administration. For both emergency and palliative use, intranasal fentanyl is available in doses of 50, 100, 200, 400(PecFent) μg.
Ultimately, Lowenthal expects an uptake of Neffy similar to nasal-spray naloxone, or Narcan, which he said accounts for 80% of use of the opioid-overdose reversal drug.
In an effort to make the drug available to more people, the Food and Drug Administration on Wednesday, March 29, approved Narcan, a nasal spray version of naloxone, to be sold over the counter ...
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