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The replication fork is a structure that forms within the long helical DNA during DNA replication. It is produced by enzymes called helicases that break the hydrogen bonds that hold the DNA strands together in a helix. The resulting structure has two branching "prongs", each one made up of a single strand of DNA.
In molecular biology, the ter site, also known as DNA replication terminus binding-site, refers to a protein domain which binds to the DNA replication terminus site. Ter-binding proteins are found in some bacterial species, and include the Tus protein which is part of the common Ter-Tus binding domain. They are required for the termination of ...
Replication terminator Tus family. Representation of the x-ray crystal structure of Tus-Ter protein-DNA complex. (Jmol rendering of coordinates from. [1] The DNA strands are shown in pink and green.) Tus, also known as terminus utilization substance, is a protein that binds to terminator sequences and acts as a counter- helicase when it comes ...
GC skew is also a statistical method for measuring strand-specific guanine overrepresentation. [1] In equilibrium conditions (without mutational or selective pressure and with nucleotides randomly distributed within the genome) there is an equal frequency of the four DNA bases (adenine, guanine, thymine, and cytosine) on both single strands of ...
Directionality (molecular biology) A furanose (sugar-ring) molecule with carbon atoms labeled using standard notation. The 5′ is upstream; the 3′ is downstream. DNA and RNA are synthesized in the 5′-to-3′ direction. Directionality, in molecular biology and biochemistry, is the end-to-end chemical orientation of a single strand of ...
The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized.
Transfer RNA. The interaction of tRNA and mRNA in protein synthesis. Transfer RNA (abbreviated tRNA and formerly referred to as sRNA, for soluble RNA[1]) is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length (in eukaryotes). [2]
Each half of the chromosome replicated by one replication fork is called a "replichore". (Graphic computer art by Daniel Yuen) A circular chromosome is a chromosome in bacteria, archaea, mitochondria, and chloroplasts, in the form of a molecule of circular DNA, unlike the linear chromosome of most eukaryotes. Most prokaryote chromosomes contain ...