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  2. Methylenetetrahydrofolate reductase deficiency - Wikipedia

    en.wikipedia.org/wiki/Methylenetetrahydrofolate...

    MTHFR is the rate-limiting enzyme in the methyl cycle, which includes the conversion of homocysteine into methionine. Defects in variants of MTHFR can therefore lead to hyperhomocysteinemia. [9] There are two common variants of MTHFR deficiency. In the more significant of the two, the individual is homozygous for the 677T polymorphism.

  3. Methylenetetrahydrofolate reductase - Wikipedia

    en.wikipedia.org/wiki/Methylenetetrahydrofolate...

    Methylenetetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene. [5] Methylenetetrahydrofolate reductase catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate , a cosubstrate for homocysteine remethylation to methionine .

  4. Microangiopathic hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Microangiopathic_hemolytic...

    Signs and symptoms [ edit ] In diseases such as hemolytic uremic syndrome , disseminated intravascular coagulation , thrombotic thrombocytopenic purpura , and malignant hypertension, the endothelial layer of small vessels is damaged with resulting fibrin deposition and platelet aggregation.

  5. Levomefolic acid - Wikipedia

    en.wikipedia.org/wiki/Levomefolic_acid

    Levomefolic acid (INN, also known as L-5-MTHF, L-methylfolate and L-5-methyltetrahydrofolate and (6S)-5-methyltetrahydrofolate, and (6S)-5-MTHF) is the primary biologically active form of folate used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine.

  6. NFL playoff scenarios: Which teams can clinch berths in Week 16?

    www.aol.com/nfl-playoff-scenarios-teams-clinch...

    One team has already joined the NFL playoff picture in Week 16, and a few more could be on the way. Here are the clinching scenarios remaining.

  7. Stem cell therapy to correct heart failure in children could ...

    www.aol.com/stem-cell-therapy-correct-heart...

    Doctors and specialists at the Murdoch Children's Research Institute in Melbourne, Australia, are studying and reprogramming the potential of the blood to treat heart failure in children.

  8. Costco issues recall for cold and flu medication over ...

    www.aol.com/costco-issues-recall-cold-flu...

    Costco has issued a recall for a cold and flu medication, sold at its stores at the end of 2024, over concerns of contamination.. The retail giant, in an advisory issued on Jan. 2, said Kirkland ...

  9. List of medical symptoms - Wikipedia

    en.wikipedia.org/wiki/List_of_medical_symptoms

    Lhermitte's sign (as if an electrical sensation shoots down back & into arms) loss of consciousness. Syncope (medicine) (R55) neck stiffness; opisthotonus; paralysis and paresis; paresthesia (R20.2) prosopagnosia; somnolence (R40.0) Obstetric / Gynaecological. abnormal vaginal bleeding. vaginal bleeding in early pregnancy / miscarriage; vaginal ...