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The cause of CIN is chronic infection of the cervix with HPV, especially infection with high-risk HPV types 16 or 18. It is thought that the high-risk HPV infections have the ability to inactivate tumor suppressor genes such as the p53 gene and the RB gene, thus allowing the infected cells to grow unchecked and accumulate successive mutations, eventually leading to cancer.
Nitroarginine, or N ω-nitro-l-arginine, also known as L-NOARG, is a nitro derivative of the amino acid arginine. [1] It is an inhibitor of nitric oxide synthase and hence a vasoconstrictor . As such, it finds widespread use as a biochemical tool in the study of nitric oxide and its biological effects.
Effects last between 45 and 180 minutes. [6] Common side effect include high blood pressure, vomiting, seizures, headache, and low blood pressure. [6] Other serious side effects include ergotism. [6] It was originally made from the rye ergot fungus but can also be made from lysergic acid.
Most side effects are direct consequences of the vasodilation and the resultant low blood pressure. They include headache ("nitrate headache") resulting from the widening of blood vessels in the brain, reflex tachycardia (fast heart rate), flush, dizziness, nausea and vomiting. These effects usually subside after a few days if the treatment is ...
In this podcast episode, Medical News Today shares three actionable resolutions that can help improve brain, heart, and metabolic health in the new year via diet, sleep, and exercise.
Higher levels of omega-6 fatty acids often found in ultraprocessed foods may interfere with the immune system’s fight against cancer cells, a new study says.
The nitrate-nitrite-nitric oxide pathway elevates nitric oxide through the sequential reduction of dietary nitrate derived from plant-based foods. [13] Nitrate-rich vegetables, in particular leafy greens, such as spinach and arugula , and beetroot , have been shown to increase cardioprotective levels of nitric oxide with a corresponding ...
Orthopedists and trauma surgeons reveal which common but dangerous activities they avoid due to the risk of injury and share tips to stay safe.