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Promethazine, sold under the brand name Phenergan among others, is a first-generation antihistamine, sedative, and antiemetic used to treat allergies, insomnia, and nausea. It may also help with some symptoms associated with the common cold [ 4 ] and may also be used for sedating people who are agitated or anxious, an effect that has led to ...
Promethazine (Pentazine, Phenergan, Promacot) can be administered via a rectal suppository, intravenous injection, oral tablet or oral suspension for adults and children over 2 years of age. Hydroxyzine (Vistaril) Cannabinoids are used in patients with cachexia, cytotoxic nausea, and vomiting, or who are unresponsive to other agents. These may ...
aspirin can cause rashes and even cause bleeding in infants. limit the use of antihistamines for long periods of time. These anti-allergy medications can cause crying, sleep problems, fussiness, excessive sleepiness in babies. Antihistamines have an effect on the amount of milk the body produces and decrease the supply.
Pheniramine (trade name Avil among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine.
Clemastine does also act as FIASMA (functional inhibitor of acid sphingomyelinase). [10] Clemastine is rapidly absorbed from the gastrointestinal tract and peak plasma concentrations are attained in 2–4 hours. Antihistamines are thought to be metabolized in the liver, mostly by mono-/didemethylation and glucuronide conjugation.
The FDA in 2015 warned that the use of codeine-containing cough medication in children may cause breathing problems. [32] Cold syrup overdose has been linked to visual and auditory hallucinations as well as rapid involuntary jaw, tongue, and eye movements in children.
When taken in prescribed quantities, codeine-promethazine is quite safe, [16] but dangers arise in higher doses since promethazine is a depressant of the central nervous system (CNS), and codeine is a respiratory depressant. When codeine is taken in very large amounts, it can cause one to stop breathing. [16]
It is expected that low doses of diphenhydramine taken occasionally will cause no adverse effects in breastfed infants. Large doses and long-term use may affect the baby or reduce breast milk supply, especially when combined with sympathomimetic drugs , such as pseudoephedrine, or before the establishment of lactation.
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