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Memory consolidation is a category of processes that stabilize a memory trace after its initial acquisition. [1] A memory trace is a change in the nervous system caused by memorizing something. Consolidation is distinguished into two specific processes.
One extensively studied anterograde amnesiac patient, codenamed H.M., demonstrated that despite his amnesia preventing him from learning new declarative information, procedural memory consolidation was still possible, albeit severely reduced in power. He, along with other patients with anterograde amnesia, were given the same maze to complete ...
The difference in memory between normal aging and a memory disorder is the amount of beta-amyloid deposits, hippocampal neurofibrillary tangles, or amyloid plaques in the cortex. If there is an increased amount, memory connections become blocked, memory functions decrease much more than what is normal for that age and a memory disorder is ...
Memory reconsolidation is a process of retrieving and altering a pre-existing long-term memory. Reconsolidation after retrieval can be used to strengthen existing memories and update or integrate new information. This allows a memory to be dynamic and plastic in nature. Just like in consolidation of memory, reconsolidation, involves the ...
The involvement of arginine and nitric oxide in memory consolidation has been confirmed in birds, mammals and other creatures, including humans. [48] Glial cells have also an important role in memory formation, although how they do their work remains to be unveiled. [49] [50] Other mechanisms for memory consolidation can not be discarded.
Some research suggests that selective amnesia may be the result of a deficit in memory consolidation. [6] Mathis and colleagues (1992) investigated the effect of protein kinase C (PKC) on the memories of rats and found that they could induce a dose-dependent deficit in memory retention. They classified this memory deficit as selective amnesia.
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A central concern in theories of memory consolidation is the role of sleep. "(O)ne set of observations suggests that consolidation may occur over any time interval, whereas another body of data suggests that these processes require sleep…. Clearly, both cannot be true.