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Feline diabetes mellitus is a chronic disease in cats whereby either insufficient insulin response or insulin resistance leads to persistently high blood glucose concentrations. Diabetes affects up to 1 in 230 cats, [1] and may be becoming increasingly common. Diabetes is less common in cats than in dogs.
The traditional subcutaneous (S.C.) insulin administration regimens used by diabetic patients fails to capture the pulsatile nature of natural insulin secretion and does not reach high enough insulin concentrations at the hepatocyte level (e.g., 10 U regular insulin injected S.C. produce a peak systemic circulation concentration of 30–40 μU ...
Trying to split this page into one for canine diabetes leaving this to become feline diabetes information. We hope 04:15, 17 March 2010 (UTC) Removing canine diabetes information as the canine information is now on the new Diabetes in dogs page. We hope 01:37, 22 March 2010 (UTC)
Basal insulin: the insulin that controls blood glucose levels between meals and overnight. It controls glucose in the fasting state. Boluses: the insulin that is released when food is eaten or to correct a high reading. Another device used in intensive insulinotherapy is the injection port. An injection port is a small disposable device ...
It is designed to improve the delivery of insulin, and is one of the earliest examples of engineered drug delivery. [3] It is used by injection under the skin once to twice a day. [1] Onset of effects is typically in 90 minutes and they last for 24 hours. [3] Versions are available that come premixed with a short-acting insulin, such as regular ...
Insulin can be injected by several methods, including a hypodermic needle, jet injector, or insulin pump. There is also inhaled insulin that can be used in adults with diabetes. [33] There are several types of insulin that are commonly used in medical practice, with varying times of onset and duration of action. [32]
The general form of this treatment is an intermediate-acting basal insulin with a regimen of food and insulin every 12 hours, with the insulin injection following the meal. [52] [67] [68] The most commonly used intermediate-acting insulins are NPH, also referred to as isophane, [69] [70] or Caninsulin, also known as Vetsulin, a porcine Lente ...
The effects of insulin vary depending on the tissue involved, e.g., insulin is most important in the uptake of glucose by muscle and adipose tissue. [ 2 ] This insulin signal transduction pathway is composed of trigger mechanisms (e.g., autophosphorylation mechanisms) that serve as signals throughout the cell.