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Bioinformatics uses biology, chemistry, physics, computer science, computer programming, information engineering, mathematics and statistics to analyze and interpret biological data. The process of analyzing and interpreting data can sometimes be referred to as computational biology , however this distinction between the two terms is often ...
The journal Nucleic Acids Research regularly publishes special issues on biological databases and has a list of such databases. The 2018 issue has a list of about 180 such databases and updates to previously described databases. [2] Omics Discovery Index can be used to browse and search several biological databases.
Bioinformatics and computational biology are interdisciplinary fields of research, development and application of algorithms, computational and statistical methods for management and analysis of biological data, and for solving basic biological problems.
Biological data has also been difficult to define, as bioinformatics is a wide-encompassing field. Further, the question of what constitutes as being a living organism has been contentious, as "alive" represents a nebulous term that encompasses molecular evolution, biological modeling, biophysics, and systems biology.
Bioinformatics, the analysis of informatics processes in biological systems, began in the early 1970s.At this time, research in artificial intelligence was using network models of the human brain in order to generate new algorithms.
The Database Issue of NAR is freely available, and categorizes many of the public biological databases. A companion database to the issue called the Online Molecular Biology Database Collection lists 1,380 online databases. [15] Other collections of databases exist such as MetaBase and the Bioinformatics Links Collection. [16] [17]
Computers in Biology and Medicine; Current Bioinformatics; Database; EMBnet.journal; Evolutionary Bioinformatics; GigaScience; IEEE/ACM Transactions on Computational Biology and Bioinformatics; Journal of the American Medical Informatics Association; Journal of Bioinformatics and Computational Biology; Journal of Biomedical Informatics; Journal ...
Popular computational models used in systems biology include process calculi, such as stochastic π-calculus, and constraint-based reconstruction and analysis (COBRA), a paradigm that considers physical, enzymatic, and topological constraints underlying a phenotype in a metabolic network.